Decoding the epigenetics and chromatin loop dynamics of androgen receptor-mediated transcription Nature Communications
From these annotated active promoters, the genes of HALLMARKS_ANDROGEN_RESPONSE from the Molecular Signature Database (MSigDB)83 were defined as AR-regulated genes. The transcriptome was divided into four quartiles, and AR-regulated genes were compared with similarly expressing genes (Supp Fig. 1A, B). Overlapping CREs to AR ChIP-seq peaks at any time point were defined as potential AR-bound enhancers.…
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